Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation

The signaling pathways governing acetaminophen (APAP)-induced liver injury have been extensively studied. However, little is known about the ubiquitin-modifying enzymes needed for the regulation of APAP-induced liver injury. Here, we examined whether the Pellino3 protein, which has E3 ligase activit...

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Detalles Bibliográficos
Autores principales: Lee, Jaewon, Ha, Jihoon, Kim, Jun-Hyeong, Seo, Dongyeob, Kim, Minbeom, Lee, Yerin, Park, Seong Shil, Choi, Dahee, Park, Jin Seok, Lee, Young Jae, Yang, Siyoung, Yang, Kyung-Min, Jung, Su Myung, Hong, Suntaek, Koo, Seung-Hoi, Bae, Yong-Soo, Kim, Seong-Jin, Park, Seok Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318043/
https://www.ncbi.nlm.nih.gov/pubmed/37258579
http://dx.doi.org/10.1038/s12276-023-01009-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318043/
https://www.ncbi.nlm.nih.gov/pubmed/37258579
http://dx.doi.org/10.1038/s12276-023-01009-w

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