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Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation
The signaling pathways governing acetaminophen (APAP)-induced liver injury have been extensively studied. However, little is known about the ubiquitin-modifying enzymes needed for the regulation of APAP-induced liver injury. Here, we examined whether the Pellino3 protein, which has E3 ligase activit...
Autores principales: | Lee, Jaewon, Ha, Jihoon, Kim, Jun-Hyeong, Seo, Dongyeob, Kim, Minbeom, Lee, Yerin, Park, Seong Shil, Choi, Dahee, Park, Jin Seok, Lee, Young Jae, Yang, Siyoung, Yang, Kyung-Min, Jung, Su Myung, Hong, Suntaek, Koo, Seung-Hoi, Bae, Yong-Soo, Kim, Seong-Jin, Park, Seok Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318043/ https://www.ncbi.nlm.nih.gov/pubmed/37258579 http://dx.doi.org/10.1038/s12276-023-01009-w |
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