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Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival

High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and the majority of cases present with metastasis and late-stage disease. Over the last few decades, the overall survival for patients has not significantly improved, and there are limited targeted treatment optio...

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Detalles Bibliográficos
Autores principales: Kotnik, Emilee N., Mullen, Mary M., Spies, Nicholas C., Li, Tiandao, Inkman, Matthew, Zhang, Jin, Martins-Rodrigues, Fernanda, Hagemann, Ian S., McCourt, Carolyn K., Thaker, Premal H., Hagemann, Andrea R., Powell, Matthew A., Mutch, David G., Khabele, Dineo, Longmore, Gregory D., Mardis, Elaine R., Maher, Christopher A., Miller, Christopher A., Fuh, Katherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318066/
https://www.ncbi.nlm.nih.gov/pubmed/37400526
http://dx.doi.org/10.1038/s42003-023-05026-3