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Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80

Acetylation of protein N-termini is one of the most common protein modifications in the eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes. The N-terminal acetyltransferase NAA80 is expressed in the animal kingdom and was recently found to specifically N-terminall...

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Detalles Bibliográficos
Autores principales: Myklebust, Line M., Baumann, Markus, Støve, Svein I., Foyn, Håvard, Arnesen, Thomas, Haug, Bengt Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318143/
https://www.ncbi.nlm.nih.gov/pubmed/37408560
http://dx.doi.org/10.3389/fchem.2023.1202501