Targeting sterol-O-acyltransferase 1 to disrupt cholesterol metabolism for cancer therapy

Cholesterol esterification is often dysregulated in cancer. Sterol O-acyl-transferase 1 (SOAT1) plays an important role in maintaining cellular cholesterol homeostasis by catalyzing the formation of cholesterol esters from cholesterol and long-chain fatty acids in cells. Many studies have implicated...

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Detalles Bibliográficos
Autores principales: Tu, Teng, Zhang, Hongying, Xu, Huanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318190/
https://www.ncbi.nlm.nih.gov/pubmed/37409263
http://dx.doi.org/10.3389/fonc.2023.1197502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318190/
https://www.ncbi.nlm.nih.gov/pubmed/37409263
http://dx.doi.org/10.3389/fonc.2023.1197502

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