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Targeting sterol-O-acyltransferase 1 to disrupt cholesterol metabolism for cancer therapy
Cholesterol esterification is often dysregulated in cancer. Sterol O-acyl-transferase 1 (SOAT1) plays an important role in maintaining cellular cholesterol homeostasis by catalyzing the formation of cholesterol esters from cholesterol and long-chain fatty acids in cells. Many studies have implicated...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318190/ https://www.ncbi.nlm.nih.gov/pubmed/37409263 http://dx.doi.org/10.3389/fonc.2023.1197502 |