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Single-cell RNA-seq Revealed that Altered Tumor Infiltrating Lymphocytes in Cirrhotic Liver Indicate Development of Hepatocellular Carcinoma

BACKGROUND AND AIMS: Cirrhosis is the precursor lesion for most hepatocellular carcinoma (HCC) cases. However, no biomarker effectively predicted HCC initiation before diagnosis by imaging. We aimed to investigate the hallmarks of immune microenvironments in healthy, cirrhotic livers and HCC tumor t...

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Detalles Bibliográficos
Autores principales: Duan, Jingxian, Zhu, Peng, Zhang, Yong, Mu, Tianhao, Li, Yingqiang, Xiong, Rui, Chen, Su, Li, Yingmei, Li, Zhicheng, Chen, Shifu, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318278/
https://www.ncbi.nlm.nih.gov/pubmed/37408821
http://dx.doi.org/10.14218/JCTH.2022.00062