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Single-cell RNA-seq Revealed that Altered Tumor Infiltrating Lymphocytes in Cirrhotic Liver Indicate Development of Hepatocellular Carcinoma
BACKGROUND AND AIMS: Cirrhosis is the precursor lesion for most hepatocellular carcinoma (HCC) cases. However, no biomarker effectively predicted HCC initiation before diagnosis by imaging. We aimed to investigate the hallmarks of immune microenvironments in healthy, cirrhotic livers and HCC tumor t...
Autores principales: | Duan, Jingxian, Zhu, Peng, Zhang, Yong, Mu, Tianhao, Li, Yingqiang, Xiong, Rui, Chen, Su, Li, Yingmei, Li, Zhicheng, Chen, Shifu, Zhang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318278/ https://www.ncbi.nlm.nih.gov/pubmed/37408821 http://dx.doi.org/10.14218/JCTH.2022.00062 |
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