The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment

INTRODUCTION: DNA double-strand breaks are the most toxic lesions repaired through the non-homologous and joining (NHEJ) or the homologous recombination (HR), which is dependent on the generation of single-strand tails, by the DNA end resection mechanism. The resolution of the HR intermediates leads...

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Detalles Bibliográficos
Autores principales: Barone, Daniela, Iannuzzi, Carmelina Antonella, Forte, Iris Maria, Ragosta, Maria Carmen, Cuomo, Maria, Dell’Aquila, Milena, Altieri, Angela, Caporaso, Antonella, Camerlingo, Rosa, Rigano, Maria Manuela, Monti, Daria Maria, Barone, Amalia, Imbimbo, Paola, Frusciante, Luigi, Monda, Marcellino, D’Angelo, Margherita, De Laurentiis, Michelino, Giordano, Antonio, Alfano, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318356/
https://www.ncbi.nlm.nih.gov/pubmed/37409248
http://dx.doi.org/10.3389/fonc.2023.1117262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318356/
https://www.ncbi.nlm.nih.gov/pubmed/37409248
http://dx.doi.org/10.3389/fonc.2023.1117262

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