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Modelling capture efficiency of single-cell RNA-sequencing data improves inference of transcriptome-wide burst kinetics
MOTIVATION: Gene expression is characterized by stochastic bursts of transcription that occur at brief and random periods of promoter activity. The kinetics of gene expression burstiness differs across the genome and is dependent on the promoter sequence, among other factors. Single-cell RNA sequenc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318389/ https://www.ncbi.nlm.nih.gov/pubmed/37354494 http://dx.doi.org/10.1093/bioinformatics/btad395 |