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Microtubule plus-end tracking proteins: novel modulators of cardiac sodium channels and arrhythmogenesis

The cardiac sodium channel Na(V)1.5 is an essential modulator of cardiac excitability, with decreased Na(V)1.5 levels at the plasma membrane and consequent reduction in sodium current (I(Na)) leading to potentially lethal cardiac arrhythmias. Na(V)1.5 is distributed in a specific pattern at the plas...

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Detalles Bibliográficos
Autores principales: Marchal, Gerard A, Galjart, Niels, Portero, Vincent, Remme, Carol Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318397/
https://www.ncbi.nlm.nih.gov/pubmed/37040608
http://dx.doi.org/10.1093/cvr/cvad052