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ASC oligomer favors caspase-1(CARD) domain recruitment after intracellular potassium efflux
Signaling through the inflammasome is important for the inflammatory response. Low concentrations of intracellular K(+) are associated with the specific oligomerization and activation of the NLRP3 inflammasome, a type of inflammasome involved in sterile inflammation. After NLRP3 oligomerization, ASC...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318405/ https://www.ncbi.nlm.nih.gov/pubmed/37402211 http://dx.doi.org/10.1083/jcb.202003053 |