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ASC oligomer favors caspase-1(CARD) domain recruitment after intracellular potassium efflux

Signaling through the inflammasome is important for the inflammatory response. Low concentrations of intracellular K(+) are associated with the specific oligomerization and activation of the NLRP3 inflammasome, a type of inflammasome involved in sterile inflammation. After NLRP3 oligomerization, ASC...

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Detalles Bibliográficos
Autores principales: Martín-Sánchez, Fátima, Compan, Vincent, Peñín-Franch, Alejandro, Tapia-Abellán, Ana, Gómez, Ana I., Baños-Gregori, María C., Schmidt, Florian I., Pelegrin, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318405/
https://www.ncbi.nlm.nih.gov/pubmed/37402211
http://dx.doi.org/10.1083/jcb.202003053