Chromosomal fusions, but not chromosomal inversions, activate a PCH-2 dependent checkpoint that promotes crossover formation in C. elegans

Meiotic crossovers promote accurate chromosome segregation during gametogenesis. In C. elegans , a highly conserved AAA ATPase, PCH-2, ensures that homologous chromosomes have at least one crossover, preventing meiotic defects. PCH-2 localizes to meiotic chromosomes and this localization is extended...

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Detalles Bibliográficos
Autores principales: Patel, Bhumil, Grobler, Maryke, Bhalla, Needhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318441/
https://www.ncbi.nlm.nih.gov/pubmed/37408786
http://dx.doi.org/10.17912/micropub.biology.000839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318441/
https://www.ncbi.nlm.nih.gov/pubmed/37408786
http://dx.doi.org/10.17912/micropub.biology.000839

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