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Precise CRISPR-Cas9-mediated mutation of a membrane trafficking domain in the Drosophila vesicular monoamine transporter gene

Monoamine neurotransmitters such as noradrenalin are released from both synaptic vesicles (SVs) and large dense-core vesicles (LDCVs), the latter mediating extrasynaptic signaling. The contribution of synaptic versus extrasynaptic signaling to circuit function and behavior remains poorly understood....

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Detalles Bibliográficos
Autores principales: Asuncion, James D., Eamani, Aditya, Rohrbach, Ethan W., Knapp, Elizabeth M., Deshpande, Sonali A., Bonanno, Shivan L., Murphy, Jeremy E., Lawal, Hakeem O., Krantz, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318446/
https://www.ncbi.nlm.nih.gov/pubmed/37409154
http://dx.doi.org/10.1016/j.crphys.2023.100101