PTBP1 promotes hepatocellular carcinoma progression by regulating the skipping of exon 9 in NUMB pre-mRNA

Aberrant alternative splicing is one of the important causes of cancer. Polypyrimidine tract binding protein 1 (PTBP1) has been found to be involved in splicing regulation in a variety of tumors. Here, we observed significant up-regulation of PTBP1 in primary hepatocellular carcinoma (HCC) tissues....

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Detalles Bibliográficos
Autores principales: He, Zhentao, Ni, Qianhua, Li, Xichun, Zhao, Mingyu, Mo, Qingguo, Duo, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318449/
https://www.ncbi.nlm.nih.gov/pubmed/37408905
http://dx.doi.org/10.1016/j.heliyon.2023.e17387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318449/
https://www.ncbi.nlm.nih.gov/pubmed/37408905
http://dx.doi.org/10.1016/j.heliyon.2023.e17387

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