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CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels

N-acyl amino acids are a large family of circulating lipid metabolites that modulate energy expenditure and fat mass in rodents. However, little is known about the regulation and potential cardiometabolic functions of N-acyl amino acids in humans. Here, we analyze the cardiometabolic phenotype assoc...

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Detalles Bibliográficos
Autores principales: Tanzo, Julia T., Li, Veronica L., Wiggenhorn, Amanda L., Moya-Garzon, Maria Dolores, Wei, Wei, Lyu, Xuchao, Dong, Wentao, Tahir, Usman A., Chen, Zsu-Zsu, Cruz, Daniel E., Deng, Shuliang, Shi, Xu, Zheng, Shuning, Guo, Yan, Sims, Mario, Abu-Remaileh, Monther, Wilson, James G., Gerszten, Robert E., Long, Jonathan Z., Benson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318452/
https://www.ncbi.nlm.nih.gov/pubmed/37121548
http://dx.doi.org/10.1016/j.jbc.2023.104764