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Adverse cardiac remodeling augments adipose tissue ß-adrenergic signaling and lipolysis counteracting diet-induced obesity

Cardiac triacylglycerol accumulation is a common characteristic of obesity and type 2 diabetes and strongly correlates with heart morbidity and mortality. We have previously shown that cardiomyocyte-specific perilipin 5 overexpression (Plin5-Tg) provokes significant cardiac steatosis via lowering ca...

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Detalles Bibliográficos
Autores principales: Kolleritsch, Stephanie, Pajed, Laura, Tilp, Anna, Hois, Victoria, Pototschnig, Isabella, Kien, Benedikt, Diwoky, Clemens, Hoefler, Gerald, Schoiswohl, Gabriele, Haemmerle, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318461/
https://www.ncbi.nlm.nih.gov/pubmed/37150323
http://dx.doi.org/10.1016/j.jbc.2023.104788