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Adverse cardiac remodeling augments adipose tissue ß-adrenergic signaling and lipolysis counteracting diet-induced obesity
Cardiac triacylglycerol accumulation is a common characteristic of obesity and type 2 diabetes and strongly correlates with heart morbidity and mortality. We have previously shown that cardiomyocyte-specific perilipin 5 overexpression (Plin5-Tg) provokes significant cardiac steatosis via lowering ca...
Autores principales: | Kolleritsch, Stephanie, Pajed, Laura, Tilp, Anna, Hois, Victoria, Pototschnig, Isabella, Kien, Benedikt, Diwoky, Clemens, Hoefler, Gerald, Schoiswohl, Gabriele, Haemmerle, Guenter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318461/ https://www.ncbi.nlm.nih.gov/pubmed/37150323 http://dx.doi.org/10.1016/j.jbc.2023.104788 |
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