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Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant

Encoded by ANK2, ankyrin-B (AnkB) is a multifunctional adapter protein critical for the expression and targeting of key cardiac ion channels, transporters, cytoskeletal-associated proteins, and signaling molecules. Mice deficient for AnkB expression are neonatal lethal, and mice heterozygous for Ank...

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Detalles Bibliográficos
Autores principales: Wallace, Michael J., Malhotra, Nipun, Mariángelo, Juan Ignacio Elio, Stevens, Tyler L., Young, Lindsay J., Antwi-Boasiako, Steve, Abdallah, Danielle, Takenaka, Sarah Sumie, Cavus, Omer, Murphy, Nathaniel P., Han, Mei, Xu, Xianyao, Mangoni, Matteo E., Hund, Thomas J., Roberts, Jason D., Györke, Sandor, Mohler, Peter J., El Refaey, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318515/
https://www.ncbi.nlm.nih.gov/pubmed/37182735
http://dx.doi.org/10.1016/j.jbc.2023.104818