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Activity of sotorasib against brain metastases from NSCLC harboring KRAS p.G12C mutation: a case report

In the CodeBreaK 100 phase 2 study, sotorasib was active for patients with metastatic non-small cell lung cancer (NSCLC) harboring Kirsten rat sarcoma viral oncogene homologue (KRAS) p.G12C mutation. However, patients with untreated and/or active brain metastases were excluded from the trial, and th...

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Detalles Bibliográficos
Autores principales: Inno, Alessandro, Marchetti, Fabiana, Valerio, Matteo, Giaj Levra, Niccolò, Alongi, Filippo, Foti, Giovanni, Gori, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AboutScience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318585/
https://www.ncbi.nlm.nih.gov/pubmed/37408855
http://dx.doi.org/10.33393/dti.2023.2593