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Pharmacological inhibition of demethylzeylasteral on JAK-STAT signaling ameliorates vitiligo

BACKGROUND: The activation of CD8(+) T cells and their trafficking to the skin through JAK-STAT signaling play a central role in the development of vitiligo. Thus, targeting this key disease pathway with innovative drugs is an effective strategy for treating vitiligo. Natural products isolated from...

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Detalles Bibliográficos
Autores principales: Chang, Yuqian, Kang, Pan, Cui, Tingting, Guo, Weinan, Zhang, Weigang, Du, Pengran, Yi, Xiuli, Guo, Sen, Gao, Tianwen, Li, Chunying, Li, Shuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318684/
https://www.ncbi.nlm.nih.gov/pubmed/37403086
http://dx.doi.org/10.1186/s12967-023-04293-2