Myofiber directs macrophages IL-10-Vav1-Rac1 efferocytosis pathway in inflamed muscle following CTX myoinjury by activating the intrinsic TGF-β signaling

BACKGROUND: To explore the role of skeletal muscle specific TGF-β signaling on macrophages efferocytosis in inflamed muscle caused by Cardiotoxin (CTX) injection. METHODS: CTX myoinjury was manipulated in TGF-βr2(flox/flox) (control) mice or transgenic mice with TGF-β receptor 2 (TGF-βr2) being spec...

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Detalles Bibliográficos
Autores principales: Liao, Zhaohong, Lan, Haiqiang, Jian, Xiaoting, Huang, Jingwen, Wang, Han, Hu, Jijie, Liao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318691/
https://www.ncbi.nlm.nih.gov/pubmed/37403092
http://dx.doi.org/10.1186/s12964-023-01163-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318691/
https://www.ncbi.nlm.nih.gov/pubmed/37403092
http://dx.doi.org/10.1186/s12964-023-01163-8

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