Cargando…

Myofiber directs macrophages IL-10-Vav1-Rac1 efferocytosis pathway in inflamed muscle following CTX myoinjury by activating the intrinsic TGF-β signaling

BACKGROUND: To explore the role of skeletal muscle specific TGF-β signaling on macrophages efferocytosis in inflamed muscle caused by Cardiotoxin (CTX) injection. METHODS: CTX myoinjury was manipulated in TGF-βr2(flox/flox) (control) mice or transgenic mice with TGF-β receptor 2 (TGF-βr2) being spec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liao, Zhaohong, Lan, Haiqiang, Jian, Xiaoting, Huang, Jingwen, Wang, Han, Hu, Jijie, Liao, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318691/ https://www.ncbi.nlm.nih.gov/pubmed/37403092 http://dx.doi.org/10.1186/s12964-023-01163-8

Ejemplares similares

IRE1α arm of unfolded protein response in muscle-specific TGF-β signaling-mediated regulation of muscle cell immunological properties
por: Xiao, Jiangwei, et al.
Publicado: (2023)

Regulatory T cells-centered regulatory networks of skeletal muscle inflammation and regeneration
por: Chen, Ziyu, et al.
Publicado: (2022)

The Vav–Rac1 Pathway in Cytotoxic Lymphocytes Regulates the Generation of Cell-mediated Killing
por: Billadeau, Daniel D., et al.
Publicado: (1998)

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
por: Villalba, Martin, et al.
Publicado: (2001)

A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia
por: Robles-Valero, Javier, et al.
Publicado: (2017)

Nε-Carboxymethyl-Lysine Negatively Regulates Foam Cell Migration via the Vav1/Rac1 Pathway
por: Bao, Zhengyang, et al.
Publicado: (2020)

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer
por: Cho, Chien-Yu, et al.
Publicado: (2016)

Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia
por: Hegde, Shailaja, et al.
Publicado: (2021)

The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1α and Glut-1 Expression and Glucose Uptake in the Brain
por: Hong, Jaewoo, et al.
Publicado: (2020)

Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation
por: Kang, In Soon, et al.
Publicado: (2020)

The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation
por: Gu, RuiCai, et al.
Publicado: (2019)

The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy
por: Graca, Flavia A., et al.
Publicado: (2022)

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis
por: Tao, Huan, et al.
Publicado: (2015)

Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity
por: Havel, Lauren S., et al.
Publicado: (2014)

A Role of Kindlin-3 in Integrin αMβ2 Outside-In Signaling and the Syk-Vav1-Rac1/Cdc42 Signaling Axis
por: Xue, Zhi-Hong, et al.
Publicado: (2013)

Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors
por: Perretta-Tejedor, Nuria, et al.
Publicado: (2017)

Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation
por: Kumar, Vijay, et al.
Publicado: (2017)

Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation
por: Teymournejad, Omid, et al.
Publicado: (2020)

Corrigendum: Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors
por: Perretta-Tejedor, Nuria, et al.
Publicado: (2018)

Vav1 Is a Component of Transcriptionally Active Complexes
por: Houlard, Martin, et al.
Publicado: (2002)

Mechanism and function of Vav1 localisation in TCR signalling
por: Ksionda, Olga, et al.
Publicado: (2012)

VAV1 Gene Polymorphisms in Patients with Rheumatoid Arthritis
por: Pawlik, Andrzej, et al.
Publicado: (2020)

Vav1 Promotes B-Cell Lymphoma Development
por: Shalom, Batel, et al.
Publicado: (2022)

Macrophage ALDH2 (Aldehyde Dehydrogenase 2) Stabilizing Rac2 Is Required for Efferocytosis Internalization and Reduction of Atherosclerosis Development
por: Zhang, Jian, et al.
Publicado: (2022)

The immuno‐reactivity of polypseudorotaxane functionalized magnetic CDMNP‐PEG‐CD nanoparticles
por: Lan, Haiqiang, et al.
Publicado: (2020)

Ubiquitin E3 Ligase MARCH7 promotes proliferation and invasion of cervical cancer cells through VAV2-RAC1-CDC42 pathway
por: Hu, Jianguo, et al.
Publicado: (2018)

VAV2 and VAV3 as Candidate Disease Genes for Spontaneous Glaucoma in Mice and Humans
por: Fujikawa, Keiko, et al.
Publicado: (2010)

Efferocytosis in the tumor microenvironment
por: Werfel, Thomas A., et al.
Publicado: (2018)

Efferocytosis and autoimmune disease
por: Kawano, Mahiru, et al.
Publicado: (2018)

Efferocytosis in multisystem diseases
por: Zhang, Yifan, et al.
Publicado: (2022)

Efferocytosis and Respiratory Disease
por: Zheng, Wenxue, et al.
Publicado: (2023)

DEL-1 promotes macrophage efferocytosis and clearance of inflammation
por: Kourtzelis, Ioannis, et al.
Publicado: (2018)

Atypical behavior of NFATc1 in cultured intercostal myofibers
por: Robison, Patrick, et al.
Publicado: (2014)

Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice
por: Tee, Jong Huat, et al.
Publicado: (2023)

Activation of RHOA–VAV1 signaling in angioimmunoblastic T-cell lymphoma
por: Fujisawa, M, et al.
Publicado: (2018)

Evaluation of Vav3.1 as prognostic marker in endometrial cancer
por: Boesch, Maximilian, et al.
Publicado: (2018)

Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output
por: Rodríguez-Fdez, Sonia, et al.
Publicado: (2019)

Helicobacter pylori CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation
por: Tegtmeyer, Nicole, et al.
Publicado: (2021)

Myofiber branching rather than myofiber hyperplasia contributes to muscle hypertrophy in mdx mice
por: Faber, Rachel M, et al.
Publicado: (2014)

Emerging Functions of ICAM-1 in Macrophage Efferocytosis and Wound Healing
por: Dalal, Prarthana J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_60i3iip44akb6v97qulhab2sc1