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Reduction of oxytocin-containing neurons and enhanced glymphatic activity in the hypothalamic paraventricular nucleus of patients with type 2 diabetes mellitus

Evidence from animal experiments has shown that the hypothalamic paraventricular nucleus (PVN) plays a key role in regulating body weight and blood glucose levels. However, it is unclear whether neuron populations in the human PVN are involved in the development of type 2 diabetes mellitus (T2DM). T...

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Detalles Bibliográficos
Autores principales: Correa-da-Silva, Felipe, Kalsbeek, Martin J., Gadella, Femke S., Oppersma, Jorn, Jiang, Wei, Wolff, Samantha E. C., Korpel, Nikita L., Swaab, Dick F., Fliers, Eric, Kalsbeek, Andries, Yi, Chun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318717/
https://www.ncbi.nlm.nih.gov/pubmed/37400893
http://dx.doi.org/10.1186/s40478-023-01606-w