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Epigenetic regulatory mechanism of ADAMTS12 expression in osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease with lacking effective prevention targets. A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAMTS12) is a member of the ADAMTS family and is upregulated in OA pathologic tissues with no fully understood molecular mech...

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Detalles Bibliográficos
Autores principales: Yang, Shu, Zhou, Xuanping, Jia, Zhen, Zhang, Mali, Yuan, Minghao, Zhou, Yizhao, Wang, Jing, Xia, Duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318776/
https://www.ncbi.nlm.nih.gov/pubmed/37400752
http://dx.doi.org/10.1186/s10020-023-00661-2