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Site-specific transgene integration in chimeric antigen receptor (CAR) T cell therapies

Chimeric antigen receptor (CAR) T cells and natural killer (NK) cells are genetically engineered immune cells that can detect target antigens on the surface of target cells and eliminate them following adoptive transfer. Recent progress in CAR-based therapies has led to outstanding clinical success...

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Detalles Bibliográficos
Autores principales: Dabiri, Hamed, Safarzadeh Kozani, Pooria, Habibi Anbouhi, Mahdi, Mirzaee Godarzee, Mohadeseh, Haddadi, Mohammad Hossein, Basiri, Mohsen, Ziaei, Vahab, Sadeghizadeh, Majid, Hajizadeh Saffar, Ensiyeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318782/
https://www.ncbi.nlm.nih.gov/pubmed/37403182
http://dx.doi.org/10.1186/s40364-023-00509-1