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Site-specific transgene integration in chimeric antigen receptor (CAR) T cell therapies
Chimeric antigen receptor (CAR) T cells and natural killer (NK) cells are genetically engineered immune cells that can detect target antigens on the surface of target cells and eliminate them following adoptive transfer. Recent progress in CAR-based therapies has led to outstanding clinical success...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318782/ https://www.ncbi.nlm.nih.gov/pubmed/37403182 http://dx.doi.org/10.1186/s40364-023-00509-1 |