Cargando…

Site-specific transgene integration in chimeric antigen receptor (CAR) T cell therapies

Chimeric antigen receptor (CAR) T cells and natural killer (NK) cells are genetically engineered immune cells that can detect target antigens on the surface of target cells and eliminate them following adoptive transfer. Recent progress in CAR-based therapies has led to outstanding clinical success...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dabiri, Hamed, Safarzadeh Kozani, Pooria, Habibi Anbouhi, Mahdi, Mirzaee Godarzee, Mohadeseh, Haddadi, Mohammad Hossein, Basiri, Mohsen, Ziaei, Vahab, Sadeghizadeh, Majid, Hajizadeh Saffar, Ensiyeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318782/ https://www.ncbi.nlm.nih.gov/pubmed/37403182 http://dx.doi.org/10.1186/s40364-023-00509-1

Ejemplares similares

Humanized Chimeric Antigen Receptor (CAR) T cells
por: Kozani, Pouya Safarzadeh, et al.
Publicado: (2021)

Novel antigens of CAR T cell therapy: New roads; old destination
por: Safarzadeh Kozani, Pooria, et al.
Publicado: (2021)

CAR-T cell therapy in T-cell malignancies: Is success a low-hanging fruit?
por: Safarzadeh Kozani, Pouya, et al.
Publicado: (2021)

Strategies for Dodging the Obstacles in CAR T Cell Therapy
por: Safarzadeh Kozani, Pooria, et al.
Publicado: (2021)

Optimizing the Clinical Impact of CAR-T Cell Therapy in B-Cell Acute Lymphoblastic Leukemia: Looking Back While Moving Forward
por: Safarzadeh Kozani, Pouya, et al.
Publicado: (2021)

Strategies for having a more effective and less toxic CAR T-cell therapy for acute lymphoblastic leukemia
por: Hashem Boroojerdi, Mohadese, et al.
Publicado: (2020)

Nanobody-based CAR-T cells for cancer immunotherapy
por: Safarzadeh Kozani, Pouya, et al.
Publicado: (2022)

T-cells engineered with a novel VHH-based chimeric antigen receptor against CD19 exhibit comparable tumoricidal efficacy to their FMC63-based counterparts
por: Nasiri, Fatemeh, et al.
Publicado: (2023)

Recent Advances in Solid Tumor CAR-T Cell Therapy: Driving Tumor Cells From Hero to Zero?
por: Safarzadeh Kozani, Pouya, et al.
Publicado: (2022)

The prevalence and impact of tension-type headache in school-aged children in Iran
por: Togha, Mansoureh, et al.
Publicado: (2023)

AS1411-functionalized delivery nanosystems for targeted cancer therapy
por: Kozani, Pooria Safarzadeh, et al.
Publicado: (2021)

CAR-T cell therapy in triple-negative breast cancer: Hunting the invisible devil
por: Nasiri, Fatemeh, et al.
Publicado: (2022)

In vivo immunotherapy of lung cancer using cross-species reactive vascular endothelial growth factor nanobodies
por: Kazemi-Lomedasht, Fatemeh, et al.
Publicado: (2017)

Marine Bacteria versus Microalgae: Who Is the Best for Biotechnological Production of Bioactive Compounds with Antioxidant Properties and Other Biological Applications?
por: Hamidi, Masoud, et al.
Publicado: (2019)

Induction of ß Cell Replication by Small Molecule-Mediated Menin Inhibition and Combined PKC Activation and TGF-ß Inhibition as Revealed by A Refined Primary Culture Screening
por: Pahlavanneshan, Saghar, et al.
Publicado: (2021)

Chimeric antigen receptor (CAR)+ T cell selection method affects transgene efficacy
por: Rushworth, David, et al.
Publicado: (2013)

Type 1 Diabetes Mellitus: Cellular and Molecular Pathophysiology at A Glance
por: Saberzadeh-Ardestani, Bahar, et al.
Publicado: (2018)

Design of a humanized anti vascular endothelial growth factor nanobody and evaluation of its in vitro function
por: Kazemi-Lomedasht, Fatemeh, et al.
Publicado: (2018)

Inducible VEGF Expression by Human Embryonic Stem Cell-Derived Mesenchymal Stromal Cells Reduces the Minimal Islet Mass Required to Reverse Diabetes
por: Hajizadeh-Saffar, E., et al.
Publicado: (2015)

Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4)
por: Sotoudeh, Nazli, et al.
Publicado: (2021)

Development of camelid monoclonal nanobody against SLC39A6 zinc transporter protein
por: Ghaderi, Hajarossadat, et al.
Publicado: (2021)

Expressing of Recombinant VEGFR2-specific Nanobody in Baculovirus Expression System
por: Shokrollahi, Narjes, et al.
Publicado: (2021)

Chimeric Antigen Receptor beyond CAR-T Cells
por: Qin, Vicky Mengfei, et al.
Publicado: (2021)

Cytomorphology of Chimeric Antigen Receptor T-Cells (CAR-T)
por: Galli, Eugenio, et al.
Publicado: (2021)

Protective responses of an engineered PspA recombinant antigen against Streptococcus pneumoniae
por: Akbari, Elaheh, et al.
Publicado: (2019)

Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
por: Benmebarek, Mohamed-Reda, et al.
Publicado: (2019)

Cancer stem cell-targeted chimeric antigen receptor (CAR)-T cell therapy: Challenges and prospects
por: Masoumi, Javad, et al.
Publicado: (2021)

A Model to Study the Phenotypic Changes of Insect Cell Transfection by Copepod Super Green Fluorescent Protein (cop-GFP) in Baculovirus Expression System
por: Shokrollahi, Narjes, et al.
Publicado: (2016)

Cell-specific targeting by engineered M13 bacteriophage expressing VEGFR2 nanobody
por: Ranjibar, Farideh, et al.
Publicado: (2018)

Metabolic and Mitochondrial Functioning in Chimeric Antigen Receptor (CAR)—T Cells
por: Rad S. M., Ali Hosseini, et al.
Publicado: (2021)

Incorporation of Immune Checkpoint Blockade into Chimeric Antigen Receptor T Cells (CAR-Ts): Combination or Built-In CAR-T
por: Yoon, Dok Hyun, et al.
Publicado: (2018)

The Effects of Chimeric Antigen Receptor (CAR) Hinge Domain Post-Translational Modifications on CAR-T Cell Activity
por: Hirobe, Sachiko, et al.
Publicado: (2022)

Exosomes Secreted by Normoxic and Hypoxic Cardiosphere-derived Cells Have Anti-apoptotic Effect
por: Namazi, Helia, et al.
Publicado: (2018)

Chimeric-Antigen-Receptor (CAR) T Cells and the Factors Influencing their Therapeutic Efficacy
por: Kravets, Victoria G, et al.
Publicado: (2017)

Regional Delivery of Chimeric Antigen Receptor (CAR) T-Cells for Cancer Therapy
por: Sridhar, Praveen, et al.
Publicado: (2017)

Modular Chimeric Antigen Receptor Systems for Universal CAR T Cell Retargeting
por: Sutherland, Ashley R., et al.
Publicado: (2020)

Innovations in cancer immunotherapy: chimeric antigen receptor T-cell therapy (CAR-T)
por: Brown, Kevin, et al.
Publicado: (2021)

Targeting gastrointestinal cancers with chimeric antigen receptor (CAR)-T cell therapy
por: Staudt, Ross E, et al.
Publicado: (2022)

Special Chimeric Antigen Receptor (CAR) Modifications of T Cells: A Review
por: Miao, Lele, et al.
Publicado: (2022)

CAR‐T‐OPENIA: Chimeric antigen receptor T‐cell therapy‐associated cytopenias
por: Taneja, Alankrita, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_q7bfoqe13dhkbosotbcfumn3e9