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Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryos

Telomeres are repetitive DNA sequences at eukaryotic chromosome ends and function in maintaining genome integrity and stability. These unique structures undergo shortening due to various factors including biological aging, consecutive DNA replication, oxidative stress, and genotoxic agents. Shortene...

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Detalles Bibliográficos
Autores principales: Tire, Betul, Ozturk, Saffet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318791/
https://www.ncbi.nlm.nih.gov/pubmed/37400833
http://dx.doi.org/10.1186/s13048-023-01211-4