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Determination of CAR T cell metabolism in an optimized protocol

Adoptive transfer of T cells modified to express chimeric antigenic receptors (CAR) has emerged as a solution to cure refractory malignancies. However, although CAR T cell treatment of haematological cancers has now shown impressive improvement in outcome, solid tumours have been more challenging to...

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Detalles Bibliográficos
Autores principales: Joaquina, Sandy, Forcados, Christopher, Caulier, Benjamin, Inderberg, Else Marit, Wälchli, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318902/
https://www.ncbi.nlm.nih.gov/pubmed/37409169
http://dx.doi.org/10.3389/fbioe.2023.1207576