Cargando…
Harnessing αβ T cell receptor mechanobiology to achieve the promise of immuno-oncology
T cell receptors (TCR) on cytolytic T lymphocytes (CTLs) recognize "foreign" antigens bound in the groove of major histocompatibility complex (MHC) molecules (H-2 in mouse and HLA in human) displayed on altered cells. These antigens are peptide fragments of proteins derived either from inf...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318960/ https://www.ncbi.nlm.nih.gov/pubmed/37339184 http://dx.doi.org/10.1073/pnas.2215694120 |