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Harnessing αβ T cell receptor mechanobiology to achieve the promise of immuno-oncology

T cell receptors (TCR) on cytolytic T lymphocytes (CTLs) recognize "foreign" antigens bound in the groove of major histocompatibility complex (MHC) molecules (H-2 in mouse and HLA in human) displayed on altered cells. These antigens are peptide fragments of proteins derived either from inf...

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Detalles Bibliográficos
Autores principales:	Reinherz, Ellis L., Hwang, Wonmuk, Lang, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10318960/ https://www.ncbi.nlm.nih.gov/pubmed/37339184 http://dx.doi.org/10.1073/pnas.2215694120

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