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High resolution monitoring of valvular interstitial cell driven pathomechanisms in procalcific environment using label-free impedance spectroscopy

INTRODUCTION: Fibro-calcific aortic valve disease has high prevalence and is associated with significant mortality. Fibrotic extracellular matrix (ECM) remodeling and calcific mineral deposition change the valvular microarchitecture and deteriorate valvular function. Valvular interstitial cells (VIC...

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Detalles Bibliográficos
Autores principales: Böttner, Julia, Werner, Sarah, Feistner, Lukas, Fischer-Schaepmann, Tina, Neussl, Katherina, Borger, Michael A., Thiele, Holger, Büttner, Petra, Schlotter, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319251/
https://www.ncbi.nlm.nih.gov/pubmed/37408660
http://dx.doi.org/10.3389/fcvm.2023.1155371