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The good and the bad of T cell cross-reactivity: challenges and opportunities for novel therapeutics in autoimmunity and cancer

T cells are main actors of the immune system with an essential role in protection against pathogens and cancer. The molecular key event involved in this absolutely central task is the interaction of membrane-bound specific T cell receptors with peptide-MHC complexes which initiates T cell priming, a...

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Detalles Bibliográficos
Autores principales: Gouttefangeas, Cécile, Klein, Reinhild, Maia, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319254/
https://www.ncbi.nlm.nih.gov/pubmed/37409132
http://dx.doi.org/10.3389/fimmu.2023.1212546