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The good and the bad of T cell cross-reactivity: challenges and opportunities for novel therapeutics in autoimmunity and cancer
T cells are main actors of the immune system with an essential role in protection against pathogens and cancer. The molecular key event involved in this absolutely central task is the interaction of membrane-bound specific T cell receptors with peptide-MHC complexes which initiates T cell priming, a...
Autores principales: | Gouttefangeas, Cécile, Klein, Reinhild, Maia, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319254/ https://www.ncbi.nlm.nih.gov/pubmed/37409132 http://dx.doi.org/10.3389/fimmu.2023.1212546 |
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