Ηigh-resolution structure of mammalian PI31–20S proteasome complex reveals mechanism of proteasome inhibition

Proteasome-catalyzed protein degradation mediates and regulates critical aspects of many cellular functions and is an important element of proteostasis in health and disease. Proteasome function is determined in part by the types of proteasome holoenzymes formed between the 20S core particle that ca...

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Detalles Bibliográficos
Autores principales: Hsu, Hao-Chi, Wang, Jason, Kjellgren, Abbey, Li, Huilin, DeMartino, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319324/
https://www.ncbi.nlm.nih.gov/pubmed/37236357
http://dx.doi.org/10.1016/j.jbc.2023.104862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319324/
https://www.ncbi.nlm.nih.gov/pubmed/37236357
http://dx.doi.org/10.1016/j.jbc.2023.104862

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