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Ηigh-resolution structure of mammalian PI31–20S proteasome complex reveals mechanism of proteasome inhibition
Proteasome-catalyzed protein degradation mediates and regulates critical aspects of many cellular functions and is an important element of proteostasis in health and disease. Proteasome function is determined in part by the types of proteasome holoenzymes formed between the 20S core particle that ca...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319324/ https://www.ncbi.nlm.nih.gov/pubmed/37236357 http://dx.doi.org/10.1016/j.jbc.2023.104862 |