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RNF43 is associated with genomic features and clinical outcome in BRAF mutant colorectal cancer

BACKGROUND: Colorectal cancer (CRC) patients with BRAF mutation have very poor prognosis. It is urgent to search for prognostic factors of BRAF mutant CRC. RNF43 is a ENF ubiquitin ligase of Wnt signaling. Mutation of RNF43 has been observed frequently in various types of human cancers. However, few...

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Detalles Bibliográficos
Autores principales: Shang, Peipei, Lu, Jiongjiong, Song, Feihong, Zhao, Yijun, Hong, Weipeng, He, Yuange, Shen, Weidong, Geng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319416/
https://www.ncbi.nlm.nih.gov/pubmed/37409251
http://dx.doi.org/10.3389/fonc.2023.1119587