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Systematic analysis of the molecular and biophysical properties of key DNA damage response factors

Repair of DNA double strand breaks (DSBs) is integral to preserving genomic integrity. Therefore, defining the mechanisms underlying DSB repair will enhance our understanding of how defects in these pathways contribute to human disease and could lead to the discovery of new approaches for therapeuti...

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Detalles Bibliográficos
Autores principales: Heyza, Joshua R, Mikhova, Mariia, Bahl, Aastha, Broadbent, David G, Schmidt, Jens C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319438/
https://www.ncbi.nlm.nih.gov/pubmed/37341699
http://dx.doi.org/10.7554/eLife.87086