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YWHAH activates the HMGA1/PI3K/AKT/mTOR signaling pathway by positively regulating Fra-1 to affect the proliferation of gastric cancer cells

Fos-related antigen 1 (Fra-1) is a nuclear transcription factor that regulates cell growth, differentiation, and apoptosis. It is involved in the proliferation, invasion, apoptosis and epithelial mesenchymal transformation of malignant tumor cells. Fra-1 is highly expressed in gastric cancer (GC), a...

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Detalles Bibliográficos
Autores principales: HE, JUNYU, ZENG, FENG, JIN, XI, LIANG, LIN, GAO, MENGXIANG, LI, WENTAO, LI, GUIYUAN, ZHOU, YANHONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tech Science Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319584/
https://www.ncbi.nlm.nih.gov/pubmed/37415737
http://dx.doi.org/10.32604/or.2023.029698