Mutations in epigenetic regulator KMT2C detected by liquid biopsy are associated with worse survival in prostate cancer patients

BACKGROUND: KMT2 (lysine methyltransferase) family enzymes are epigenetic regulators that activate gene transcription. KMT2C is mainly involved in enhancer-associated H3K4me1, and is also one of the top mutated genes in cancer (6.6% in pan-cancer). Currently, the clinical significance of KMT2C mutat...

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Detalles Bibliográficos
Autores principales: ZHU, SHA, XU, NANWEI, LIANG, JIAYU, ZHAO, FENGNIAN, WANG, ZILIN, NI, YUCHAO, DAI, JINDONG, ZHAO, JINGE, ZHANG, XINGMING, CHEN, JUNRU, SUN, GUANGXI, SHEN, PENGFEI, ZENG, HAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tech Science Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319590/
https://www.ncbi.nlm.nih.gov/pubmed/37415738
http://dx.doi.org/10.32604/or.2023.028321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319590/
https://www.ncbi.nlm.nih.gov/pubmed/37415738
http://dx.doi.org/10.32604/or.2023.028321

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