The engineered single guide RNA structure as a biomarker for gene-editing reagent exposure

CRISPR arrays and CRISPR-associated (Cas) proteins comprise a prevalent adaptive immune system in bacteria and archaea. These systems defend against exogenous parasitic mobile genetic elements. The adaption of single effector CRISPR-Cas systems has massively facilitated gene-editing due to the repro...

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Detalles Bibliográficos
Autores principales: Ryan, Emmarie C., Huggins, Leslie M., Podlevsky, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319717/
https://www.ncbi.nlm.nih.gov/pubmed/37402738
http://dx.doi.org/10.1038/s41598-023-37525-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319717/
https://www.ncbi.nlm.nih.gov/pubmed/37402738
http://dx.doi.org/10.1038/s41598-023-37525-y

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