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IRAK3-mediated suppression of pro-inflammatory MyD88/IRAK signaling affects disease severity in acute pancreatitis

Acute pancreatitis (AP), which is characterized by self-digestion of the pancreas by its own prematurely activated digestive proteases, is a major reason for hospitalization. The autodigestive process causes necrotic cell death of pancreatic acinar cells and the release of damage associated molecula...

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Detalles Bibliográficos
Autores principales: Thiel, Franziska G., Asgarbeik, Saeedeh, Glaubitz, Juliane, Wilden, Anika, Lerch, Markus M., Weiss, Frank Ulrich, Sendler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319718/
https://www.ncbi.nlm.nih.gov/pubmed/37402858
http://dx.doi.org/10.1038/s41598-023-37930-3