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Biocompatible topical delivery system of high-molecular-weight hyaluronan into human stratum corneum using magnesium chloride

Non-invasive delivery of hyaluronan into the stratum corneum (SC) is extremely difficult because of its high molecular weight and the strong barrier of the SC. We developed a safe method of administering hyaluronan into the human SC and determined its penetration route. The amount of hyaluronan that...

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Detalles Bibliográficos
Autores principales: Fujii, Mika Y., Okishima, Anna, Ichiwata, Hiroko S., Oka, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319798/
https://www.ncbi.nlm.nih.gov/pubmed/37402762
http://dx.doi.org/10.1038/s41598-023-37718-5