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Biocompatible topical delivery system of high-molecular-weight hyaluronan into human stratum corneum using magnesium chloride
Non-invasive delivery of hyaluronan into the stratum corneum (SC) is extremely difficult because of its high molecular weight and the strong barrier of the SC. We developed a safe method of administering hyaluronan into the human SC and determined its penetration route. The amount of hyaluronan that...
Autores principales: | Fujii, Mika Y., Okishima, Anna, Ichiwata, Hiroko S., Oka, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319798/ https://www.ncbi.nlm.nih.gov/pubmed/37402762 http://dx.doi.org/10.1038/s41598-023-37718-5 |
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