Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN

Circular RNAs (circRNAs) are a regulatory RNA class. While cancer-driving functions have been identified for single circRNAs, how they modulate gene expression in cancer is not well understood. We investigate circRNA expression in the pediatric malignancy, neuroblastoma, through deep whole-transcrip...

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Detalles Bibliográficos
Autores principales: Fuchs, Steffen, Danßmann, Clara, Klironomos, Filippos, Winkler, Annika, Fallmann, Jörg, Kruetzfeldt, Louisa-Marie, Szymansky, Annabell, Naderi, Julian, Bernhart, Stephan H., Grunewald, Laura, Helmsauer, Konstantin, Rodriguez-Fos, Elias, Kirchner, Marieluise, Mertins, Philipp, Astrahantseff, Kathy, Suenkel, Christin, Toedling, Joern, Meggetto, Fabienne, Remke, Marc, Stadler, Peter F., Hundsdoerfer, Patrick, Deubzer, Hedwig E., Künkele, Annette, Lang, Peter, Fuchs, Jörg, Henssen, Anton G., Eggert, Angelika, Rajewsky, Nikolaus, Hertwig, Falk, Schulte, Johannes H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319804/
https://www.ncbi.nlm.nih.gov/pubmed/37402719
http://dx.doi.org/10.1038/s41467-023-38747-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319804/
https://www.ncbi.nlm.nih.gov/pubmed/37402719
http://dx.doi.org/10.1038/s41467-023-38747-4

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