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Progranulin is an FMRP target that influences macroorchidism but not behaviour in a mouse model of Fragile X Syndrome

A growing body of evidence has implicated progranulin in neurodevelopment and indicated that aberrant progranulin expression may be involved in neurodevelopmental disease. Specifically, increased progranulin expression in the prefrontal cortex has been suggested to be pathologically relevant in male...

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Detalles Bibliográficos
Autores principales: Life, Benjamin, Bettio, Luis E.B., Gantois, Ilse, Christie, Brian R., Leavitt, Blair R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319828/
https://www.ncbi.nlm.nih.gov/pubmed/37416094
http://dx.doi.org/10.1016/j.crneur.2023.100094