Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

Alterations in metabolism are a hallmark of cancer. It is unclear if oxidative phosphorylation (OXPHOS) is necessary for tumour cell survival. In this study, we investigated the effects of severe hypoxia, site-specific inhibition of respiratory chain (RC) components, and uncouplers on necrotic and a...

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Detalles Bibliográficos
Autores principales: Doczi, Judit, Karnok, Noemi, Bui, David, Azarov, Victoria, Pallag, Gergely, Nazarian, Sara, Czumbel, Bence, Seyfried, Thomas N., Chinopoulos, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319846/
https://www.ncbi.nlm.nih.gov/pubmed/37402778
http://dx.doi.org/10.1038/s41598-023-37677-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319846/
https://www.ncbi.nlm.nih.gov/pubmed/37402778
http://dx.doi.org/10.1038/s41598-023-37677-x

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