The fourth vaccination with a non-SARS-CoV-2 variant adapted vaccine fails to increase the breadth of the humoral immune response

Escape mutations in the spike protein of SARS-CoV-2 are a major reason for Omicron breakthrough infections. After basal vaccination only very low titers of Omicron neutralizing antibodies are present. However, booster vaccinations induce higher titers against the Omicron variant. The neutralization...

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Detalles Bibliográficos
Autores principales: Hein, Sascha, Sabino, Catarina, Benz, Nuka Ivalu, Görgülü, Esra, Maier, Thorsten Jürgen, Oberle, Doris, Hildt, Eberhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319856/
https://www.ncbi.nlm.nih.gov/pubmed/37402816
http://dx.doi.org/10.1038/s41598-023-38077-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319856/
https://www.ncbi.nlm.nih.gov/pubmed/37402816
http://dx.doi.org/10.1038/s41598-023-38077-x

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