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Production and properties of adhesin-free gingipain proteinase RgpA

The Arg-specific gingipains of Porphyromonas gingivalis RgpA and RgpB have 97% identical sequences in their catalytic domains yet their propeptides are only 76% identical. RgpA isolates as a proteinase–adhesin complex (HRgpA) which hinders direct kinetic comparison of RgpA(cat) as a monomer with mon...

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Detalles Bibliográficos
Autores principales: Mahmud, Abu Sayeed M., Seers, Christine A., Huq, N. Laila, Zhang, Lianyi, Butler, Catherine A., Moore, Caroline, Cross, Keith J., Reynolds, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319874/
https://www.ncbi.nlm.nih.gov/pubmed/37402780
http://dx.doi.org/10.1038/s41598-023-37534-x