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T cell receptor signaling strength establishes the chemotactic properties of effector CD8(+) T cells that control tissue-residency

Tissue-resident memory (T(RM)) CD8(+) T cells are largely derived from recently activated effector T cells, but the mechanisms that control the extent of T(RM) differentiation within tissue microenvironments remain unresolved. Here, using an IFNγ-YFP reporter system to identify CD8(+) T cells execut...

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Detalles Bibliográficos
Autores principales: Abdelbary, Mahmoud, Hobbs, Samuel J., Gibbs, James S., Yewdell, Jonathan W., Nolz, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319879/
https://www.ncbi.nlm.nih.gov/pubmed/37402742
http://dx.doi.org/10.1038/s41467-023-39592-1